The Extending Network of FOXO Transcriptional Target Genes
نویسندگان
چکیده
منابع مشابه
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متن کاملThe ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation.
FoxO (forkhead box O; forkhead members of the O class) are transcription factors that function under the control of insulin/insulin-like signalling. FoxO factors have been associated with a multitude of biological processes, including cell-cycle, cell death, DNA repair, metabolism and protection from oxidative stress. Central to the regulation of FoxO factors is a shuttling system, which confin...
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ژورنال
عنوان ژورنال: Antioxidants & Redox Signaling
سال: 2011
ISSN: 1523-0864,1557-7716
DOI: 10.1089/ars.2010.3419